DNA methylation analysis kit (MspI/HpaII), EpiJET™

Supplier: Thermo Fisher Scientific
Fermentas EpiJET™
K1441EA 143 EUR
K1441
DNA methylation analysis kit (MspI/HpaII), EpiJET™
Nucleic Acid Reagents Restriction Enzymes
5-Methylcytosine is a prominent epigenetic DNA modification which plays an important role in regulation of gene expression. The EpiJET™ DNA Methylation Analysis Kit (MspI/HpaII) uses the MspI and HpaII restriction enzymes to analyse DNA methylation status at a specific locus. Epi MspI and Epi HpaII are isoschizomers with differing sensitivities to CpG methylation. When the internal CpG in the 5’-CCGG-3’ tetranucleotide sequence is methylated, cleavage with Epi HpaII is blocked, but cleavage with Epi MspI is not affected. The Epi MspI and Epi HpaII enzymes are specially formulated for epigenetics studies to complete genomic DNA digestion in 1 hour.

  • Fast: Complete digestion of genomic DNA in 1 hour at 37 °C
  • Efficient: Specially formulated enzymes for epigenetic studies of DNA methylation status

Delivery information: Each kit includes Epi Mspl: 200 µl, Epi HpaII: 200 µl, 10X EpiBuffer: 1 ml, Control pUC19/SmaI DNA unmethylated (0,5 µg/µl): 20 µl, Control pUC19/SmaI DNA CpG methylated (0,5 µg/µL): 20 µl.
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