Anti-ABL1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Supplier: Bioss
BOSSBS-10355R-A647EA 450 EUR
BOSSBS-10355R-A647
Anti-ABL1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antibodies
The c Abl proto oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c Abl proto oncogene undergoes a (9;22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c Abl sequences from chromosome 9 to the Bcr gene on chromosome 22. The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ABL1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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