Anti-POLK Rabbit Polyclonal Antibody (Cy5®)

Supplier: Bioss
Anti-POLK Rabbit Polyclonal Antibody (Cy5®)
DNA polymerase lambda (pol lambda), also designated DNA polymerase lambda or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol lambda is a member of the DNA polymerase type-X family. Pol lambda extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol ?may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol lambda and thus influences the ability of pol ?to synthesize DNA.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: POLK
Clonality: Polyclonal
Conjugation: Cy5®
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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